DL/POホスファチジルコリンについて
文献
1. Yaguchi T, Nagata T, Nishizaki T . 1-Palmitoyl-2-oleoyl-sn-glycero- 3-phosphocholine improves cognitive decline by enhancing long-term depression. Behav. Brain Res. 204: 129-132 (2009).
2. Matsuyama S, Matsumoto A, Enomoto T, Nishizaki T . Activation of
nicotinic acetylcholine receptors induces long-term potentiation in
vivo in the intact mouse dentate gyrus. Eur. J. Neurosci. 12: 3741-3747 (2000).
3. Miyamoto H, Yaguchi T, Ohta K, Nagai K, Nagata T, Yamamoto S, Nishizaki T . 2-pyrrolidinone induces a long-lasting facilitation of
hippocampal synaptic transmission by enhancing α7 ACh receptor
responses via a PKC pathway. Mol. Brain Res. 117: 91-96 (2003).
4. Nishizaki T, Nomura T, Matuoka T, Kondoh T, Enikolopo G,
Sumikawa K, Watabe S, Shiotani T, Yoshii M. The anti-dementia drug
nefiracetam facilitates hippocampal synaptic transmission by
functionally targeting presynaptic nicotinic ACh receptors. Mol. Brain
Res. 80: 53-62 (2000).
5. Nishizaki T, Nomura T, Matsuyama S, Kondoh T, Fujimoto E, Yoshii
M. Critical role of presynaptic nicotinic ACh receptor in the formation
of long-term potentiation: implication of development of
anti-dementia drug. Psychogeriatrics 1: 209-217 (2001).
6. Nishizaki T, Nomura T, Matsuoka T, Tsujishita Y. Arachidonic acid as a messenger for the expression of long-term potentiation. Biochem.
Biophys. Res. Commun. 254: 446-449 (1999).
7. Ikeuchi Y, Nishizaki T , Matsuoka T, Sumikawa K. Arachidonic acid
potentiates ACh receptor currents by protein kinase C activation but
not by receptor phosphorylation. Biochem. Biophys. Res. Commun.
221: 716-721 (1996).
8. Nishizaki T, Ikeuchi Y, Matsuoka T, Sumikawa K, Short-term
depression and long-term enhancement of ACh-gated channel
currents induced by linoleic and linolenic acid. Brain Res. 751:
253-258 (1997).
9. Nishizaki T, Matsuoka T, Nomura T, Sumikawa K. Modulation of ACh
receptor currents by arachidonic acid. Mol. Brain Res. 57: 173-179
(1998).
10. Nishizaki T, Nomura T, Matsuoka T, Enikolopov G, Sumikawa K.
Arachidonic acid induces a long-lasting facilitation of hippocampal
synaptic transmission by modulating PKC activity and nicotinic ACh
receptors. Mol. Brain Res. 69: 263-272 (1999).
11. Nomura T, Nishizaki T , Enomoto T, Itoh H. A long-lasting facilitation of hippocampal neurotransmission via a phospholipase A2 signaling pathway. Life Sci. 68: 2885-2891 (2001).
12. Yaguchi T, Yamamoto S, Nagata T, Kanno T, Tanaka A,Nishizaki T .
Effects of cis-unsaturated free fatty acids on PKC-ε activation and
nicotinic ACh receptor responses. Mol. Brain Res. 133: 320-324
(2005).
13. Ikeuchi Y, Nishizaki T , Matsuoka T, Sumikawa K. Long-lasting
enhancement of ACh receptor currents by lysophospholipids. Mol.
Brain Res. 45: 317-320 (1997).
14. Nishizaki T, Sumikawa K. Lysophosphatidic acid potentiates ACh
receptor currents by G-protein-mediated activation of protein kinase
C. Mol. Brain Res. 50: 121-126 (1997). 15. Yaguchi T, Nagata T, Nishizaki T . Dilinoleoylphosphatidylcholine
ameliorates scopolamine-induced impairment of spatial learning and
memory by targeting alpha7 nicotinic ACh receptors. Life Sci. 84:
263-266 (2009).
先端生体情報研究機構 監修